Themes and Topics

A transformative exploration of metallomics in Human Health, Environmental Health, Emerging Enabling Technologies, and Sustainability & Regeneration.

Join us at ISM9 for a transformative exploration of metallomics in four major themes: Human HealthEnvironmental HealthEmerging Enabling Technologies, and Sustainability & Regeneration. Gain valuable insights into the critical relationship between metals and human health, from population-level impacts to the development of cutting-edge diagnostics and therapeutics. Discover the intricate natural cycles of metals, their impact on ecosystems, and sustainable solutions, and explore the latest transformative technologies shaping the future of metallomics research.

Join us to employ metallomics for gaining valuable insights into the critical relationship between metals and human health. Dive into a comprehensive exploration of metallomics, encompassing population-level impacts in public and occupational health studies, mechanistic research on infectious and non-communicable diseases, advancements in metal-based diagnostics & therapeutics, and the role of metals in promoting healthy ageing.

Health & Disease

Metals are key players in morbidity and mortality, affecting crucial biological processes associated with onset, progression, and exacerbation of diseases. Explore their roles across a range of conditions including cardiovascular, respiratory, and neurological diseases, diabetes and cancer, with an additional focus on genetic diseases from protein mutations affecting metal homeostasis. Uncover the intricate relationship between changes in metal handling during normal ageing, systemic and organ-specific inflammation, oxidative stress, and their implications for health. Unravel the role of metals in infectious disease risk, shedding light on the interplay between changes in the microbiome microvirome and adverse biological responses in the pathways to chronic illness.

Areas include:

  • Ageing & life cycle
  • Metal metabolic & genetic disorders
  • Disease states
  • Infectious disease

Public & Occupational Health

Beyond traditional high-level exposures, there is growing recognition that long-term, chronic exposure to seemingly low levels of metals imposes significant health burdens on the population. Hear the latest research examining the health impacts of metals from various sources such as diet, food, air, and water on national and global scales, with a focus on widening the scope of metallomics to facilitate interaction with occupational health specialists and epidemiologists engaged in these vital areas of study.

Areas include:

  • Public health impacts of metals across the life course
  • Metal toxicity & carcinogenesis

Diagnostics & Therapeutics

These interdisciplinary sessions will converge inorganic chemistry, cell and molecular biology, chemical biology, advanced spectroscopies, biophysics, nuclear medicine, medicinal chemistry, and more. Discover how the intrinsic properties of metals and inorganic materials can be harnessed to revolutionise drug development, agents for disease diagnosis, imaging and new treatment modalities with a strong clinical and translational focus, unveiling the new frontiers of this rapidly evolving field.

Areas include:

  • Metallodrugs
  • Chelation therapies
  • Novel imaging technologies
  • Radionuclide imaging and therapy
  • Nano-chemistry & nanotherapeutics

Join us in a journey as we explore metallomics in emerging discoveries and new methodological developments that unravel the intricate natural cycles of metals and metalloids across environmental spheres and examine their disruption by human activities. Discover the fate & transport of metals, their bioavailability, and the potential repercussions on broader ecosystems & public health whilst exploring sustainable solutions for metal recycling and recovery.

Biogeochemical Cycles

Examine the behaviour of chemical elements within soils, sediments, water, and air, delving into the biological processes and factors that govern their mobilisation. Discover the potential of metal isotopes in tracing the biogeochemical cycles of elements, shedding light on source-sink processes of metal pollution and their biogeochemical behaviours. Uncover insights into the management and remediation of metal-contaminated land, sediments and water, while exploring the pivotal role of bioavailability in risk assessment and regulatory decision-making.

Areas include:

  • Enzymology & bioinorganic chemistry of geochemical cycles
  • Metal speciation & dynamics in the environment
  • Biogeochemical modelling of chemical elements
  • Anthropogenic disturbances of elemental cycles

Metal Ecotoxicology & Homeostasis

Explore the ecological implications of metal toxicity on biodiversity and productivity within aquatic and terrestrial environments. Unravel the complexity of metal bioavailability in all varieties of organisms and plant life. Discover the role of sentinel species in revealing environmental metal contamination with the associated adverse outcome pathways linked to toxicity, and how this understanding can be used to re-evaluate the ecological risks posed by metal contamination to integrate into environmental policies and regulations.

Areas include:

  • Aquatic and terrestrial metal pollution
  • Plant metal metabolism
  • Sentinel species & metal toxicity pathways
  • Risk assessment of emerging metal contaminant

Metal Bio-recovery & Remediation

Discover sustainable approaches to recycle and recover metals from soils and sediments affected by mining, industrial, agricultural and fishing activities. Explore the identification of potential environmental hazards and their impact on ecosystems, including human, plant and microbial populations, along with effective remediation techniques. Uncover the application of metals in green chemistry and renewable biomaterials for zero-waste solutions.

Areas include:

  • Sustainable metal bio-recovery techniques
  • Novel remediation strategies
  • Metals in green chemistry and renewable biomaterials

Gain insight into the latest emerging technologies for transformative breakthroughs and interdisciplinary discoveries in metallomics research. Learn about the innovative approaches in applied bioinorganic chemistry, novel instrumentation, and transformative technology that are pivotal in shaping the field. Discover how these remarkable technological advancements, when applied across disciplines, are unveiling exciting horizons for the future of metallomics.

Transformative Technology & Method Development

Explore the refinement and integration of analytical instrumentation and computational advancements, including machine learning and artificial intelligence, to unravel complex questions and enhance our capabilities to handle large datasets and achieve greater sample throughput. Gain insight into new possibilities of multi-omics approaches and the necessary infrastructure for collaborative, multidisciplinary science. Understand how the integration of metallomics into our ‘omics’ scientific portfolio underscores the power of multi-modal approaches in the field.

Areas include:

  • Advances in instrumentation
  • Bioinformatics and AI
  • Multi-omics workflows
  • Speciomics
  • Single cell technologies
  • Isotopic fingerprints in metallomics

Theoretical & Applied Bioinorganic Chemistry

Delve into how bioinorganic chemistry plays a pivotal role in advancing the development of technologies with significant real-world impact. Highlights include metallosensing to enable precise analysis and understanding of metal-related processes in human and environmental health, metal catalysis for efficient and sustainable chemical transformations in the pharmaceutical and energy sectors, as well as the intricate interplay between metals and their redox properties, for the development of advanced biomaterials in energy and sustainability applications.

Areas include:

  • Metallosensing
  • Design of metal probes and development of biomarkers
  • Metal catalysis
  • Metal redox chemistry

Join us in our quest to tackle 21st-century challenges by delving into the transformative power of metallomics across the crucial sectors of energy & transport, biotechnology, and circular economy. Uncover the health impact of non-exhaust metal emissions in low-carbon transportation alternatives, discover how metallomics drives sustainable biomaterial production, and explore sustainable practices throughout the entire metal cycle.

Energy & Transport

A shift away from traditional combustion engines is expected to mitigate CO2 emissions and alleviate air pollution’s impact on public health. Whilst emerging technologies do address tailpipe emissions, explore emerging concerns regarding the health consequences of non-exhaust metal emissions, as well as the burden of “clean energy technologies” on the demand for critical minerals in metal catalysts to enhance fuel efficiency. Hear the latest evidence of health impacts, toxicological mechanisms, and how metallomics can be used in concert with more traditional approaches to engage in strategies for integrating health and toxicological assessments into the production of safe, smart and sustainable advanced materials.

Areas include:

  • Planes, trains and automobiles – metal emissions & health effects
  • Metals in net zero energy
  • Metals in catalysis

Biotechnology

In a changing global climate, increasing water scarcity and security, and population growth are placing a significant burden on our essential resources and forcing us to explore novel solutions. Investigate how metallomics can enhance soil quality, preserve a thriving soil microbiome, optimise essential element nutrition, minimize loss of biodiversity, and offer effective pesticide solutions for sustainable food production. Delve into the complexities of food production in regions affected by metal contamination and explore the pivotal role of metals in the development of next-generation sustainable materials, including cutting-edge nanotechnologies across diverse industries.

Areas include:

  • Sustainable food production
  • Microbial metallomics
  • Sustainable production of pharmaceuticals & industrial chemicals
  • Inorganic nanomaterials in advanced manufacturing of biomaterials

Circular Economy

Metals play a crucial role in the circular economy of nations. To meet growing demand and address metal scarcity, there is a need to prioritise their recovery and reuse. Examine current and emerging sustainable practices encompassing metal extraction, manufacturing, recycling and reuse, utilising thoughtful product design and supportive regulations that maximise the advantages of a circular economy.

Areas include:

  • Sustainable metal lifecycle management
  • Responsible consumption & new materials design
  • Integration of chemical & biomolecular processes

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